Excess weight mediates changes in HDL pool that reduce cholesterol efflux capacity and increase antioxidant activity

Obesity-related decline in high-density lipoprotein (HDL) functions such as cholesterol efflux capacity (CEC) has supported the notion that this lipoprotein dysfunction may contribute for atherogenesis among obese patients. We investigated if potentially other HDL protective actions may be affected with weight gain and these changes may occur even before the obesity range in a cross-sectional analysis.

Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - September 22, 2019 Category: Nutrition Authors: Jose Carlos de Lima-Junior, Vitor W.M. Virginio, Filipe A. Moura, Adriana Bertolami, Marcelo Bertolami, Otavio R. Coelho-Filho, Ilaria Zanotti, Wilson Nadruz, Eliana Cotta de Faria, Luiz Sergio F. de Carvalho, Andrei C. Sposito Source Type: research