Decreased expression of TRAAK channels in Hirschsprung ’s disease: a possible cause of postoperative dysmotility

ConclusionsTRAAK gene expression is significantly downregulated in HSCR colon, suggesting a role for these ion channels in colonic neurotransmission.TRAAK downregulation within ganglionic specimens highlights the dysfunctional nature of ganglia in this region.

http://link.springer.com/10.1007/s00383-019-04572-4

Source: Pediatric Surgery International - September 20, 2019 Category: Surgery Source Type: research