Involvement of Upregulated P53-Induced Death Domain Protein in Retinal Ganglion Cells Apoptosis after Optic Nerve Crush.

CONCLUSIONS: Taken together, PIDD may play a crucial role in RGCs apoptosis after ONC, and this process may be relevant to caspase-2 and tBid.
PMID: 31533600 [PubMed - as supplied by publisher]

Source: Current Molecular Medicine - September 17, 2019 Category: Molecular Biology Authors: Zhang M, Chen L, Xu F, Jiang L, Yan W, Kunwar B, Tang F, Yang K, Shen C, Huang H, Lv J, Qin C, Wu X, Zeng S, Li M, Zhong S, Chen Q Tags: Curr Mol Med Source Type: research