[Nocardiosis as a Differential Diagnosis of Pulmonary Epitheloid Cell Granulomas].

[Nocardiosis as a Differential Diagnosis of Pulmonary Epitheloid Cell Granulomas]. Pneumologie. 2019 Sep;73(9):538-543 Authors: Acar A, Niemeyer D, Groß-Fengels W, Bachmann M, Wiest G Abstract A 47-year-old man presented with fever, weight loss and pulmonary consolidations and cavitation in the x-ray of the thorax. The comprehensive diagnostics resulted pulmonary epitholoid cell granulomas, therefore an immunosuppressive therapy was applied on suspicion of sarcoidosis. Progressivly the pulmonary infiltration increased and cerebral and abdominal abscesses were determined with microbiological detection of Nocardia farcinica. Despite antibiotic therapy, the patient died in a septic shock with multiple organ failure.Nocardiosis is a rare granulomatous bacterial infectious disease. Risk factors include immunosuppression and structural lung diseases. Characteristic is an abscess formation that can occur in any organ, while pulmonary onset is common.The case demonstrates the importance of considering rare differential diagnoses in the detection of pulmonary epithelioid granulomas. PMID: 31533175 [PubMed - in process]
Source: Pneumologie - Category: Respiratory Medicine Tags: Pneumologie Source Type: research