Psychosis in Borrelia burgdorferi infection - part I: epidemiology, pathogenesis, diagnosis and treatment of neuroborreliosis.

Psychosis in Borrelia burgdorferi infection - part I: epidemiology, pathogenesis, diagnosis and treatment of neuroborreliosis. Psychiatr Pol. 2019 Jun 30;53(3):629-640 Authors: Brodziński S, Nasierowski T Abstract Borreliosis is a multisystem, bacterial, zoonotic infectious disease with diversified spectrumof symptoms, which may also include psychotic disorders. Clinical picture of the disease is often unspecific, which makes the diagnosis relatively difficult. Uncharacteristic process of borreliosis is a result of complex molecular strategies used by spirochetes to infect, disseminate and survive in host organism. Part I of the article is focused on the current knowledge about pathogenesis of Lyme Borreliosis (LB), especially neuroborreliosis. Additionally, epidemic situation in Poland and in Europe was presented. Also, typical clinical manifestations of LB were described. In the article, the crucial pathogenic cell mechanisms were depicted. The processes of infection and dissemination of Borrelia in host were presented. The most important strategies of evading the response of host immune system were also discussed. These mechanisms are probable cause of the chronic and uncharacteristic clinical picture of the disease, as they significantly impair host immune response to bacteria. Also, there were presented molecular processes of neural cells impairment, which may lead to observed clinical symptoms of neuroborreliosis. Furthermore, diagnostic methods, t...
Source: Psychiatria Polska - Category: Psychiatry Tags: Psychiatr Pol Source Type: research

Related Links:

Authors: Arab JP, Dirchwolf M, Álvares-da-Silva MR, Barrera F, Benítez C, Castellanos-Fernandez M, Castro-Narro G, Chavez-Tapia N, Chiodi D, Cotrim H, Cusi K, de Oliveira CPMS, Díaz J, Fassio E, Gerona S, Girala M, Hernandez N, Marciano S, Masson W, Mendez-Sanchez N, Leite N, Lozano A, Padilla M, Panduro A, Paraná R, Parise E, Perez M, Poniachik J, Restrepo JC, Ruf A, Silva M, Tagle M, Tapias M, Torres K, Vilar-Gomez E, Costa Gil JE, Gadano A, Arrese M Abstract Non-alcoholic fatty liver disease (NAFLD) currently represents an epidemic worldwide. NAFLD is the most frequently diagnosed chr...
Source: Annals of Hepatology - Category: Gastroenterology Tags: Ann Hepatol Source Type: research
Publication date: 15 February 2021Source: Personality and Individual Differences, Volume 170Author(s): Marta Malesza, Magdalena Claudia Kaczmarek
Source: Personality and Individual Differences - Category: Psychiatry & Psychology Source Type: research
In this study, we present the results of using different geochemical backgrounds (BG1 –BG3) to establish the level of heavy metal pollution in street dust in Warsaw, Poland. We applied individual and collective indicators calculated with respect to the following backgrounds: (1) upper continental crust (UCC) (BG1), (2) the regional geochemical background established for Quaternary surface deposits of the Mazovian region (Poland) (parent geological material occurring in the studied area, Warsaw, Poland) (BG2), and (3) the minimal values of the concentration of heavy metals determined for the real street dust sample co...
Source: Environmental Geochemistry and Health - Category: Environmental Health Source Type: research
After being epidemic in China, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) infection has rapidly spread in many countries as a global pandemic, with the number of affected cases dramatically increasing worldwide on a daily basis. Although the median age of hospitalized patients with confirmed infection is usually more advanced 1, with older age reported to be associated to higher mortality rate 2, physiological adaptations occurring during pregnancy have been claimed to be potentially responsible for a more severe respiratory disease, thus leading to higher rates of maternal and fetal complications 3,4.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Correspondence Source Type: research
Conclusion: The results of our study did not support associations between MMP1, MMP9, COL1A1, and COL1A2 genetic variants with the risk of thoracic artery disease in Polish patients. However, rs1799750 MMP1 and rs3918242 MMP9 seem to be associated with the degree of aortic regurgitation. PMID: 33029260 [PubMed - in process]
Source: Disease Markers - Category: Laboratory Medicine Tags: Dis Markers Source Type: research
Authors: Stanhope J, Weinstein P PMID: 33029790 [PubMed - as supplied by publisher]
Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
On Oct. 1, New York state released an app that can notify you if you’ve come into contact with a person who has tested positive for COVID-19. Called “COVID Alert NY,” the app is one of 10 currently active in states around the U.S. that are based on Google and Apple’s decentralized contact tracing system, which was developed to maintain privacy while also giving health authorities a potentially powerful new tool to clamp down on outbreaks of the virus. “Everybody’s wondering, ‘I was next to this person, I was next to that person,’ but this can actually give you some data,&rdqu...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 feature Londontime Source Type: news
Open letter calling for new Covid-19 strategy also signed by ‘Prof Cominic Dummings’Coronavirus – latest updatesSee all our coronavirus coverageAn open letter that made headlines calling for a herd immunity approach to Covid-19 lists a number of apparently fake names among its expert signatories, including “Dr Johnny Bananas” and “Professor Cominic Dummings”.TheGreat Barrington declaration, which was said to have been signed by more than 15,000 scientists and medical practitioners around the world, was found by Sky News to contain numerous false names, as well as those of several h...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak Health UK news Science Epidemics Politics Health policy Infectious diseases Society Medical research World news US news Source Type: news
Conditions:   Virus-HIV;   Covid19 Intervention:   Other: questionnaire Sponsor:   Tourcoing Hospital Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This morning, I awoke to find that I had been copied on dozens of Twitter message exchanges among several people who were discussing the pathology of Borrelia burgdorferi, the bacterium that causes Lyme disease, among human beings and mice. My first thought was "Seriously?! It's too early for this!" My second thought was "well, David, your Twitter sure has evolved from your pre-Lyme days when you used it mostly to promote vapid celebrity interviews." As I began my morning caffeine ritual and read through each of the messages, I gained a new appreciation for some of the real complexities of "in...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
More News: Borrelia | Brain | Epidemics | Epidemiology | Infectious Diseases | Lyme Disease | Neurology | Poland Health | Psychiatry | Zoonoses