Assessment of Acute Motor Effects and Tolerance Following Self-Administration of Alcohol and Edible THC in Adolescent Male Mice.

CONCLUSIONS: Adolescent mice self-administered both alcohol and edible THC to a degree sufficient to acutely impact locomotor activity. However, only edible THC consumption had lasting effects during short-term abstinence. Thus, this adolescent co-use model could be used to explore sex differences in self-administration as well as the impact substance co-use might have on other domains such as mood and cognition. PMID: 31524960 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31524960?dopt=Abstract

Source: Alcoholism, Clinical and Experimental Research - September 15, 2019 Category: Addiction Authors: Smoker MP, Hernandez M, Zhang Y, Boehm SL Tags: Alcohol Clin Exp Res Source Type: research