Propofol Anesthesia Alters Spatial and Topologic Organization of Rat Brain Metabolism

Conclusions The data revealed anesthesia-related alterations in spatial and topologic organization of metabolic brain network, as well as a close relationship between metabolic connectivity and cerebral metabolism during propofol anesthesia. These findings may provide novel insights into the metabolic mechanism of anesthetic-induced loss of consciousness.
Source: Anesthesiology - Category: Anesthesiology Source Type: research