Thymine DNA Glycosylase (TDG) is a Key Regulator of CaMKII γ Expression and Vascular Smooth Muscle Phenotype.
This study indicates that CaMKIIg expression in VSM is regulated by cytosine methylation/demethylation and that TDG is an important determinant of this process and, more broadly, VSM phenotype switching and function.
PMID: 31518169 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Heart and Circulatory Physiology - Category: Physiology Authors: Liu Y, Sun LY, Singer DV, Ginnan R, Zhao W, Jourd'heuil FL, Jourd'heuil D, Long X, Singer HA Tags: Am J Physiol Heart Circ Physiol Source Type: research