Aortic valve calcium score as a predictor for outcome after TAVI using the CoreValve revalving system

Abstract: Background: TAVI is a novel treatment option for patients at too high risk for surgery. Risk scores for surgical valve replacement failed to accurately predict outcomes after TAVI and alternative risk parameters are lacking so far.Objective: We evaluated the CT-derived aortic valve calcification score as a predictor for outcome during and after TAVI.Methods: Transfemoral TAVI using the CoreValve device was performed in 68 patients, in whom the aortic valve calcium score was determined from preprocedural 64-sclice ECG gated CT-scans.Results: 30-day MACE rate (death, stroke, MI) was 10.3%, 1-year mortality was 11.8%. Using linear regression analysis the aortic valve calcium score was the only significant predictor for 30-day MACE and for 1-year mortality and was also associated with the incidence and severity of post procedural aortic regurgitation (r=0.33, p750 had a significant lower 1-year survival rate compared to patients with scores

Source: International Journal of Cardiology - December 26, 2011 Category: Cardiology Authors: Alexander W. Leber, Markus Kasel, Thomas Ischinger, Ulrich H. Ebersberger, Diethmar Antoni, Martin Schmidt, Gotthard Riess, Vivian Renz, Armin Huber, Thomas Helmberger, Ellen Hoffmann Tags: Original Articles Source Type: research