Risk factors predisposing to psychotic symptoms during levetiracetam therapy: A retrospective study

ConclusionOur retrospective study found that psychotic symptoms during LEV therapy were significantly associated with status epilepticus, a history of psychotic symptoms, a history of psychiatric illness other than psychosis, and concomitant PHT usage, whereas concomitant LTG usage was protective. Psychotic symptoms specifically as an adverse drug reaction to LEV were significantly associated with female gender, intellectual disability, status epilepticus, and a history of psychotic symptoms.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research