The role of CB1-receptors in the proconvulsant effect of leptin on penicillin-induced epileptiform activity in rats.

CONCLUSIONS: This study provides electrophysiological evidence that the proconvulsant activity of leptin is mediated, at least in part, by inhibition of cannabinoids in the experimental model of epilepsy. PMID: 23521910 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/23521910?dopt=Abstract

Source: CNS Neuroscience and Therapeutics - April 1, 2013 Category: Neuroscience Authors: Arslan G, Alici SK, Ayyildiz M, Agar E Tags: CNS Neurosci Ther Source Type: research