Characterization of RHD locus polymorphism in D negative and D variant donors from Northwestern Argentina.

CONCLUSIONS: A RHD genotyping strategy for patients and donors from Northwestern Argentina must consider the detection of the frequently found RHD*01N.75, RHD*DEL43, and RHD*weak D type 93 variants. Taking into account that RHD*DEL43 has scarcely been found in North Americans and Europeans whereas RHD*01N.75 and RHD*weak D type 93 have never been described in populations other than Argentineans, these RHD variants could be attributed to Native Amerindian genetic influence.
PMID: 31503349 [PubMed - as supplied by publisher]

Source: Transfusion - September 9, 2019 Category: Hematology Authors: Trucco Boggione C, Nogués N, González-Santesteban C, Mufarrege N, Luján Brajovich M, Mattaloni SM, Leri M, Biondi C, Muñiz-Diaz E, Castilho L, Cotorruelo C Tags: Transfusion Source Type: research