Enzymatic and molecular characterisation of leucine aminopeptidase of Burkholderia pseudomallei

Conclusions: This study showed that LAP is a secretory product of B. pseudomallei with features similar to LAP of other organisms. Identification of major LAP sequence types of B. pseudomallei was made possible based on RFLP analysis of the pepA gene. The high LAP activity detected in both B. pseudomallei and B. thailandensis, suggests that LAP is probably a housekeeping enzyme rather than a virulence determinant.
Source: BMC Microbiology - Latest articles - Category: Microbiology Authors: Source Type: research