UCLA-led research reveals potential treatments for deadly tropical disease
Melioidosis is a tropical disease that claims an estimated 90,000 lives worldwide each year. There is no vaccine, and current treatments are hampered by the ability of the bacterium that causes the disease to resist even the strongest antibiotics.Hardy and lethal, that bacterium, Burkholderia pseudomallei, is classified by the Centers for Disease Control and Prevention as a potential bioweapon.UCLA-led research has identified two compounds that, based on tests on human cells and on mice, show potential for treating melioidosis. One is a widely used drug already approved by the U.S. Food and Drug Administration as an antifu...
Source: UCLA Newsroom: Health Sciences - September 11, 2019 Category: Universities & Medical Training Source Type: news
Products Approved for Other Bioterrorism Emergencies
U.S. Food and Drug Administration. 09/08/2017 This Web page lists products approved for seven bioterrorism emergencies: Botulism due to Clostridium botulinum toxin; Ebola Virus Disease (EVD); Glanders and Melioidosis due to Burkholderia mallei and B. pseudomallei, respectively; Plague due to Yersinia pestis; Smallpox due to Variola major and Variola minor; Tularemia due to Francisella tularensis; and Zika Virus Disease. (Text) (Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - May 9, 2018 Category: International Medicine & Public Health Authors: The U.S. National Library of Medicine Source Type: news
Determination of the Persistence of Non-Spore-Forming Biological Threat Agents in the Environment
U.S. Environmental Protection Agency, Office of Research and Development, National Homeland Security Research Center. 12/07/2015This 35-page report presents the results of an investigation to evaluate the persistence (or natural attenuation) of Yersinia pestis (Y. pestis), Francisella tularensis (F. tularensis), and Burkholderia mallei (B. mallei) on glass and soil under multiple environmental conditions and time points. This generation of scientifically defensible persistence data is useful for the proper planning of decontamination efficacy tests and for formulation of response or remediation plans in preparation for pos...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - January 17, 2016 Category: Global & Universal Authors: The U.S. National Library of Medicine Source Type: news