Microstructural abnormality in white matter, regulatory T lymphocytes, and depressive symptoms after stroke

ConclusionsFA reductions in the anterior limb of the internal capsule cause abnormality in the frontal‐subcortical circuits and confer a biological vulnerability, which in combination with environmental stressors results in the onset of depression. Our findings also demonstrated the possibility of preventing post‐stroke depression by targeting the role of regulatory T lymphocytes in brain tissue repair and regeneration after stroke.

Source: Psychogeriatrics - December 12, 2014 Category: Geriatrics Authors: Fumihiko Yasuno, Akihiko Taguchi, Akihide Yamamoto, Katsufumi Kajimoto, Hiroaki Kazui, Takashi Kudo, Akie Kikuchi‐Taura, Atsuo Sekiyama, Toshifumi Kishimoto, Hidehiro Iida, Kazuyuki Nagatsuka Tags: ORIGINAL ARTICLE Source Type: research