Diet and nutrition: An important risk factor in leprosy

Publication date: Available online 4 September 2019Source: Microbial PathogenesisAuthor(s): Ved Prakash Dwivedi, Arindam Banerjee, Indraneel Das, Aparajita Saha, Malabika Dutta, Bhavya Bhardwaj, Saptarshi Biswas, Debprasad ChattopadhyayAbstractLeprosy, once considered as poor man's disease may cause severe neurological complications and physical disabilities. Classification of leprosy depends upon the cell mediated and humoral immune responses of the host, from tuberculoid to lepromatous stage. Current therapy to prevent the disease is not only very lengthy but also consists of expensive multiple antibiotics in combination. Treatment and the duration depend on the bacillary loads, from six months in paucibacillary to a year in multibacillary leprosy. Although as per WHO recommendations, these antibiotics are freely available but still out of reach to patients of many rural areas of the world. In this review, we have focused on the nutritional aspect during the multi-drug therapy of leprosy along with the role of nutrition, particularly malnutrition, on susceptibility of Mycobacterium leprae and development of clinical symptoms. We further discussed the diet plan for the patients and how diet plans can affect the immune responses during the disease.
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research

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Semin Neurol 2019; 39: 462-471 DOI: 10.1055/s-0039-1687884Leprosy is a challenging international health concern. Despite tremendous efforts in reducing worldwide disease prevalence in the past decades, some countries remain endemic and are plagued by high levels of disability. The neurological complications of leprosy are varied and complex, with current research focused on evaluating tools for earlier diagnosis of neuropathy, especially in resource-limited countries. While treatment with multidrug therapy is highly effective, active research aims to simplify regimens to improve adherence, minimize adverse effects, and pre...
Source: Seminars in Neurology - Category: Neurology Authors: Tags: Review Article Source Type: research
Yohei Sasakawa, chair of The Nippon Foundation and World Health Organisation (WHO) Goodwill Ambassador for Leprosy Elimination, delivered a keynote address at the 20th International Leprosy Congress (ILC). Credit: Stella Paul/IPSBy Stella PaulMANILA, Sep 11 2019 (IPS) Forty years ago, Yohei Sasakawa saw his father moved to tears after meeting and witnessing the suffering of people affected by leprosy – also known as Hansen’s disease. Not only did the patients have a physical illness, but they also suffered from social exclusion and discrimination. It made the young Sasakawa vow to work for the elimination of le...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Active Citizens Aid Asia-Pacific Civil Society Conferences Development & Aid Editors' Choice Featured Global Headlines Health Human Rights Regional Categories TerraViva United Nations Global Forum of People’s Organisations on Source Type: news
Jennifer Quimno of the Coalition of Leprosy Advocates of the Philippines (CLAP) (centre) is joined by Sri Lanka's Shagana Thiygalingam (L) and Amarasinghe Manjula (R) after Quimno delivered the recommendations presented by the Global Forum of People's Organisations on Hansen's Disease to the International Leprosy Congress in Manila on September 11. Credit: Ben Kritz/IPSBy Ben KritzMANILA, Sep 11 2019 (IPS) Stronger government action to fight stigma and discrimination, more government funding for health and non-health support programmes, and a larger role for people’s organisations in developing policy towards Hansen&...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Asia-Pacific Civil Society Conferences Development & Aid Featured Global Headlines Health Human Rights Regional Categories TerraViva United Nations Global Forum of People’s Organisations on Hansen’s Disease Hansen's disease N Source Type: news
By Sasakawa Health Foundation - The Nippon FoundationMANILA, PHILIPPINES, Sep 7 2019 (IPS-Partners) World Health Organization’s (WHO) Goodwill Ambassador for Leprosy Elimination and recipient of the 2019 Order of the Rising Sun as well as the 2018 Gandhi Peace Prize, Mr. Yohei Sasakawa, is in the Philippines to call on academics, medical stakeholders and those affected by the disease to unite towards “Zero Leprosy”.  Mr. Sasakawa, chairperson of The Nippon Foundation (TNF) – one of Japan’s largest private organisations – is attending two key global conferences on the disease being h...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Health Source Type: news
by Laura Dean, Rachel Tolhurst, Gartee Nallo, Karsor Kollie, Anthony Bettee, Sally Theobald BackgroundIntegrated disease management, disability and inclusion (DMDI) for NTDs is increasingly prioritised. There is limited evidence on the effectiveness of integrated DMDI from the perspective of affected individuals and how this varies by differing axes of inequality such as age, gender, and disability. We used narrative methods to consider how individuals ’ unique positions of power and privilege shaped their illness experience, to elucidate what practical and feasible steps could support integrated DMDI in Liberia and ...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
ConclusionsThe resulting data demonstrate that leprosy amongst the elderly deserves attention because of the increased susceptibility to disability in this age group, with their higher risk of reaction and their greater level of co-morbidity.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
(a) Chronic trophic ulcers (CTU) especially located over plantar region are leading cause of deformity and disability in Hansen ’s patients. Despite various treatment modalities available, it’s quite chronic and refractory to treatment. The successful use of topical insulin in various types of wounds led us to evaluate its safety and efficacy in the treatment of chronic trophic ulcers over the plantar region. (b) Forty t wo patients released from treatment of leprosy were recruited and randomized in two groups.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Wound Healing and Tissue Remodelling Source Type: research
RESUMO: Introdu ção: O Tocantins é o estado mais hiperendêmico para hanseníase no Brasil. Objetivo: Descrever as características epidemiológicas e tendências temporais dos indicadores da hanseníase em menores de 15 anos de idade no Tocantins entre 2001-2012. Metodologia: Análise de dados do Sistema de Informação de Agravos de Notificação (SINAN). Incluíram-se casos novos de menores de 15 anos residentes no estado. Calcularam-se os indicadores e analisaram-se as tendências temporais por meio da regressão joi...
Source: Revista Brasileira de Epidemiologia - Category: Epidemiology Source Type: research
This systematic review and meta-analysis of 32 studies assesses the strength of evidence linking clinical features and sex of patients with leprosy to disability.
Source: JAMA Dermatology - Category: Dermatology Source Type: research
CONCLUSIONS A downward trend for the detection coefficients in the general population and in individuals under 15 years old was found in Maranh ão. Despite this result, the rates are still very high, demanding efforts from all spheres of public administration and health professionals to reduce the burden of the disease in the state.RESUMO OBJETIVO Analisar a tend ência temporal dos indicadores da hanseníase em estado brasileiro hiperendêmico, no período de 2011 a 2015. MÉTODOS Trata-se de um estudo de série temporal dos indicadores de hanseníase no estado do Maranh&atil...
Source: Revista de Saude Publica - Category: International Medicine & Public Health Source Type: research
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