Postnatal delayed growth impacts cognition but rescues programmed impaired pulmonary vascular development in an IUGR rat model

Intrauterine growth restriction (IUGR) is a state of slower fetal growth usually followed by a catch-up growth. Postnatal catch-up growth in IUGR models increases the incidence of pulmonary arterial hypertension in adulthood. Here, we hypothesize that the adverse pulmonary vascular consequences of IUGR may be improved by slowing down postnatal growth velocity. Meanwhile, cognitive function was also studied.

Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - August 29, 2019 Category: Nutrition Authors: LingLing Yan, Yu Wang, ZiMing Zhang, ShanShan Xu, Rahim Ullah, XiaoFei Luo, XueFeng Xu, XiaoLu Ma, Zheng Chen, LiYan Zhang, Ying Lv, LiZhong Du Source Type: research