Precision mice as infection models
Mice are important animal models for studying human pathogens, but they have limitations: not all human viruses replicate in mice and often these animals do not reproduce aspects of disease and immune responses. Mice implanted with human bone marrow, liver, and thymus (BLT mice) develop human immune systems, but most pathogens infect other cell types. […]
Source: virology blog - Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information BLT mouse human cytomegalovirus humanized mouse immunosuppressed mouse lung implant lung only transplant mouse mouse model viral viruses Source Type: blogs
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