Resveratrol improves osteogenic differentiation of senescent bone mesenchymal stem cells through inhibiting endogenous reactive oxygen species production via AMPK activation.

Conclusion: These results provide a potential mechanism involving AMPK activation/ROS inhibition signaling pathway in osteogenic differentiation of BMSCs enhanced by resveratrol. It suggests that development of therapy towards ROS is an effective way for osteoporosis treatment. PMID: 31438780 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31438780?dopt=Abstract

Source: Redox Report : communications in free radical research - August 25, 2019 Category: Biochemistry Authors: Zhou T, Yan Y, Zhao C, Xu Y, Wang Q, Xu N Tags: Redox Rep Source Type: research