Ischemia and reperfusion injury following cardioplegic arrest is attenuated by age and testosterone deficiency in male but not female mice

ConclusionsAlthough age had no effect on susceptibility to I/R injury after cardioplegic arrest in females, it actually protected against injury in older males. Our findings indicate that low testosterone may be protective against I/R injury following cardioplegic arrest in older males.

http://link.springer.com/10.1186/s13293-019-0256-4

Source: Biology of Sex Differences - August 22, 2019 Category: Biology Source Type: research