Increased markers of cardiac vagal activity in leucine-rich repeat kinase 2-associated Parkinson ’s disease

ConclusionsIncreased beat-to-beat HRV inLRRK2 G2019S mutation carriers compared with controls and idiopathic PD patients may indicate augmented cardiac autonomic cholinergic activity, suggesting early impairment of central vagal feedback loops in LRRK2-associated PD.

http://link.springer.com/10.1007/s10286-019-00632-w

Source: Clinical Autonomic Research - August 22, 2019 Category: Research Source Type: research