Anti-pan-neurofascin IgG3 as a marker of fulminant autoimmune neuropathy

Conclusions Our results indicate that anti–pan-NF-associated neuropathy differs from anti–NF-155-associated neuropathy, and epitope and subclass play a major role in the pathogenesis and severity of anti–NF-associated neuropathy and should be determined to correctly classify patients, also in respect to possible differences in therapeutic response.

http://nn.neurology.org/cgi/content/short/6/5/e603?rss=1

Source: Neurology Neuroimmunology and Neuroinflammation - August 15, 2019 Category: Neurology Authors: Stengel, H., Vural, A., Brunder, A.-M., Heinius, A., Appeltshauser, L., Fiebig, B., Giese, F., Dresel, C., Papagianni, A., Birklein, F., Weis, J., Huchtemann, T., Schmidt, C., Körtvelyessy, P., Villmann, C., Meinl, E., Sommer, C., Leypoldt, F., Do Tags: Autoimmune diseases, All Clinical Neurology, Guillain-Barre syndrome, Chronic inflammatory demyelinating polyneuropathy Article Source Type: research