Irreversible electroporation ablation of end-stage metastatic retroperitoneal lesions: Report on three cases and literature review.

Irreversible electroporation ablation of end-stage metastatic retroperitoneal lesions: Report on three cases and literature review. Exp Ther Med. 2019 Sep;18(3):2243-2249 Authors: Jiang T, Zhao Q, Tian G, Chen X, Wu L Abstract Metastatic retroperitoneal tumors constitute an end-stage disease with poor prognosis that represents a heavy global health burden. The present study aimed to explore the efficacy of irreversible electroporation ablation (IRE) therapy in patients with end-stage retroperitoneal tumors. Between April 2016 and September 2017, three patients with unresectable retroperitoneal malignant tumors were enrolled. Among these cases, ultrasound (US)-guided IRE was palliatively performed for targeting 3 tumors (1 tumor per patient) located around the abdominal aorta. Post-treatment contrast-enhanced US (CEUS) and contrast-enhanced computed tomography (CECT) scans were subsequently performed to evaluate the area adjacent to the ablation zone and determine the prognosis. During the follow-up, the cases experienced a reduction of pain (mean score of 5.8 decreased to 2.2, based on the visual analogue scale), and had an overall survival rate ranging from 2 to 11 months. Case 1 remained alive at the time of submission of this study, but case 2 died within 2 months and case 3 within 11 months due to liver metastases of the primary tumor. At the 3-week follow-up, the CEUS image for case 1 exhibited a contrast defect with a sufficient ablation margin, in ...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research

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Publication date: Available online 11 September 2019Source: Annals of Medicine and SurgeryAuthor(s): Ayad Ahmad Mohammed, Sardar Hassan ArifAbstractSitus inversus is a condition in which the anatomical viscera are placed in a reverse anatomical location, it may be partial affecting the thoracic organs or the abdominal organs, or total affecting both.A 28-year-old man who was a known case of situs inversus totalis presented with epigastric pain and left hypochondrial pain. ultrasound revealed multiple gall stones in a left-sided gall bladder, laparoscopic cholecystectomy done successfully for him with no complications.Patie...
Source: Annals of Medicine and Surgery - Category: General Medicine Source Type: research
DiscussionMalignant peripheral nerve sheath tumors (MPNST) are uncommon sarcomatous tumors that are believed to be derived from Schwann cell or neighboring cells with perineurial differentiation. MTT is rarely reported in mediastinum, lung and heart (
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
We present an extremely rare case of a 3-year-old child with a primary carcinoid tumor of the prostate. A 3-year-old boy presented with failure to thrive, constipation, recurrent respiratory tract infections, and pain in the genital area. His karyotype was normal and cystic fibrosis and coeliac disease were excluded prior to further investigation. An abdominopelvic computed tomography scan revealed a prostatic mass. Transrectal ultrasound-guided prostate biopsy was therefore performed and pathological examination revealed a carcinoid tumor.
Source: Urology - Category: Urology & Nephrology Authors: Tags: Pediatric Case Reports Source Type: research
We present an extremely rare case of a 3-year-old child with a primary carcinoid tumour of the prostate. A 3-year-old boy presented with failure to thrive, constipation, recurrent respiratory tract infections and pain in the genital area. His karyotype was normal and cystic fibrosis and coeliac disease were excluded prior to further investigation. An abdominopelvic CT scan revealed a prostatic mass. Transrectal ultrasound-guided prostate biopsy was therefore performed and pathological examination revealed a carcinoid tumour.
Source: Urology - Category: Urology & Nephrology Authors: Source Type: research
Conclusionsplenic lymphangioma is rare and benign tumor. Total splenectomy under laparotomy or laparoscopy is the appropriate treatment.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
ConclusionAlthough very rare, solitary fibrous tumor of the adrenal gland should be considered in differential diagnosis of adrenal masses.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Written by Pendell MeyersI texted this Prehospital ECG with no clinical information to Dr. Smith.What do you think?Dr. Smith texted back " Pulmonary Embolism " within seconds.Here is the clinical information:A woman in her 30s with no known past medical history presented by ambulance for altered mental status and syncope. She was delirious, ill-appearing, hypotensive, tachycardic, afebrile, satting 99% on 2L/min masal cannula.Sinus tachycardiaAcute RV strain pattern evidenced by the morphology of the QRS and T-wave in V1-V3, including small-moderate R-wave followed by deep S-wave, then concave ST segment into who...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
ConclusionThe management of PCI may be challenging particularly in the presence of pneumoperitoneum. Complications must be excluded before considering a conservative therapy. Therefore, PCI should be interpreted with relevance to the entire clinical context.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Authors: Altomare M, Cimbanassi S, Chiara O, Salvi PF Abstract OBJECTIVES: Evaluate Alvarado Score's (AS) accuracy related with C-reactive protein (CRP). Evaluate the accuracy rate of ultrasonography (US). MATERIALS AND METHODS: We analyzed data on 290 patients admitted to Emergency Department (ED) of Sant'Andrea Hospital (Rome - Italy) presenting abdominal pain in lower quadrants between Jan2009-Apr2015. AS, laboratory tests, images and report from CT-scan and US were collected. Histological examination is considered as Gold Standard. We calculated Specificity(Sp), Sensitivity(Se), Accuracy(Ac), positive predi...
Source: Annali Italiani di Chirurgia - Category: Surgery Tags: Ann Ital Chir Source Type: research
A 46-year-old black woman with a history of endometriosis presented with right-sided sciatica, right shoulder pain and persistent cough. She had a history of severe endometriosis and fibroids with previous laparoscopic supracervical hysterectomy and bilateral salpingectomy performed at an outside facility one year earlier. Three weeks prior to presentation, she had a spontaneous right pneumothorax which was managed with a tube thoracostomy. Transvaginal ultrasound demonstrated bilateral endometriomas and repeat computed tomography scan indicated a recurrent right apical pneumothorax.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: Original Article Source Type: research
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