CONFIRMATION OF DAMAGING EFFECT OF MSH2 c.2634+1G > C MUTATION ON SPLICING, ITS CLASSIFICATION AND IMPLICATIONS FOR COUNSELING

Lynch Syndrome (LS) is a hereditary cancer syndrome which is characterized by the most frequent cancer localizations in colorectum and endometrium. Aside from familial aggregation of cancer, the striking hallmarks of this hereditary cancer syndrome are early diagnosis of these two types of carcinomas (

Source: Cancer Genetics and Cytogenetics - August 13, 2019 Category: Genetics & Stem Cells Authors: Rakobradovi ć Jelena, Krivokuća Ana, Jovandić Stevo, Kesić Vesna, Branković-Magić Mirjana Tags: Original Article Source Type: research