Childhood and Adolescent Migraine Prevention (CHAMP) Study: A Double‐Blinded, Placebo‐Controlled, Comparative Effectiveness Study of Amitriptyline, Topiramate, and Placebo in the Prevention of Childhood and Adolescent Migraine

ConclusionsThe goal of the CHAMP study is to obtain level 1 evidence for the effectiveness of amitriptyline and topiramate in the prevention of migraine in children and adolescents. If this study proves to be positive, it will provide information to the practicing physician as how to best prevent migraine in children and adolescents and subsequently improve the disability and outcomes.

Source: Headache: The Journal of Head and Face Pain - April 17, 2013 Category: Neurology Authors: Andrew D. Hershey, Scott W. Powers, Christopher S. Coffey, Dixie D. Eklund, Leigh Ann Chamberlin, Leslie L. Korbee, Tags: Protocols Source Type: research