MicroRNA-29a suppresses the invasion and migration of osteosarcoma cells by regulating the SOCS1/NF- κB signalling pathway through negatively targeting DNMT3B.

In conclusion, miR‑29a promoted the apoptosis, and inhibited the invasion, migration and EMT process of OS cells via inhibition of the SOCS1/NF‑κB signalling pathway by directly targeting DNMT3B.
PMID: 31364725 [PubMed - as supplied by publisher]

Source: International Journal of Molecular Medicine - July 23, 2019 Category: Molecular Biology Authors: Gong HL, Tao Y, Mao XZ, Song DY, You D, Ni JD Tags: Int J Mol Med Source Type: research