Nivolumab ‐induced celiac‐like enteropathy in patient with metastatic renal cell carcinoma: Case report and review of the literature

Nivolumab may induce severe celiac ‐like enteropathy, that may appear very rapidly, after only two injections of nivolumab, and may be successfully treated with corticosteroids. This observation underlines the importance of histological analysis of duodenal biopsies and the necessity to rule out a real celiac disease in patients wi th nivolumab‐induced diarrhea. AbstractNivolumab may induce severe celiac ‐like enteropathy, that may appear very rapidly, after only two injections of nivolumab, and may be successfully treated with corticosteroids. This observation underlines the importance of histological analysis of duodenal biopsies and the necessity to rule out a real celiac disease in patients wi th nivolumab‐induced diarrhea.

Source: Clinical Case Reports - July 27, 2019 Category: General Medicine Authors: Lucie Duval, Sarah Habes, Thierry Chatellier, Pascale Guerzider, C éline Bossard, Claude Masliah, Isabelle Archambeaud, Yann Touchefeu, Tamara Matysiak‐Budnik Tags: CASE REPORT Source Type: research