Carcinosarcoma of the hand.

Carcinosarcoma of the hand.
Dermatol Online J. 2019 Jun 15;25(6):
Authors: Gamret AC, Fertig RM, Klingbeil KD, Satahoo S, Kerr DA, Romanelli P, Miteva M, Rodgers SE
Abstract
Carcinosarcomas are rare malignant tumors derived of both epithelial and mesenchymal elements. Herein, we report an elderly man originally diagnosed with a squamous cell carcinoma of the hand. Upon excision, the tumor was found to be a more aggressive carcinosarcoma. Immunohistochemical stains revealed that the sarcoma component of the lesion was vimentin positive, whereas the primary carcinoma tumor cells were positive for p63 and CK903. Both components were negative for CD34 and D2-40. This tumor was found to have angiolymphatic invasion and eventually metastasized to the axillary lymph nodes and lungs.
PMID: 31329397 [PubMed - in process]

Source: Dermatol Online J - June 14, 2019 Category: Dermatology Authors: Gamret AC, Fertig RM, Klingbeil KD, Satahoo S, Kerr DA, Romanelli P, Miteva M, Rodgers SE Tags: Dermatol Online J Source Type: research