A newly identified missense mutation in CLCA2 is associated with autosomal dominant cardiac conduction block.

CONCLUSION: Our findings indicate that a novel heterozygous missense mutation c.G1725T of the CLCA2 gene may be associated with heart block disease and the mutation in this gene may lead to sinus node lesions and conduction blocking.
PMID: 31326550 [PubMed - as supplied by publisher]

Source: Gene - July 17, 2019 Category: Genetics & Stem Cells Authors: Mao Z, Wang Y, Peng H, He F, Zhu L, Huang H, Huang X, Lu X, Tan X Tags: Gene Source Type: research