Does HLA sharing cause pregnancy losses ?

I recently heard from one of my friend who is going through IVF to have her child. In the course of her treatment , she went through two pregnancy losses, one at 12 weeks and one at 5 weeks. As usual, a battery of tests were performed on her by her IVF specialist to find out where the fault lay- why did the miscarriage happen ? Of the several tests performed on her, two tests came back positive. She was told her NK cells in uterus are elevated ; and that her HLA haplotype (what the heck is that?) was very similar to her husband's. On seeing her results, her doctor told her that it was a waste of time and energy in trying to get pregnant via IVF. He told her that she would never succeed in carrying a baby to term ; and that she needs a surrogate to carry the baby. This was a great shock for a woman who was already going through hell in order to have a baby ? Going through IVF is a physically and emotionally draining pursuit. Facing a miscarriage after successful IVF is heart-wrenching. In this situation, how will you react when you are told that there are some killer cells in your uterus which are waiting to devour your precious embryo ? How would you feel when a doctor tells you that you share so much in common with your husband that you cannot carry a baby to term ? Normally, when someone tells you that you have something in common with your partner , you feel happy , but now there is a person telling you that too much sharing means that your joy of ha...
Source: The Patient's Doctor - Category: Obstetricians and Gynecologists Tags: Natural killer cell In vitro fertilisation Uterus Miscarriage ivf Pregnancy Manju Infant Source Type: blogs