Effects of Royal Jelly Administration on Lipid Profile, Satiety, Inflammation, and Antioxidant Capacity in Asymptomatic Overweight Adults.

Conclusion: Compared with the placebo, RJ supplementation demonstrated a statistically significant decrease in total cholesterol (6.7%; p=0.041) and inflammatory marker C-reactive protein (19%; p=0.027), whereas significant increases were observed in anti-inflammatory marker adiponectin (34%; p=0.011), endogenous antioxidants bilirubin (35%; p=0.002) and uric acid (5%; p=0.018), total antioxidant capacity in serum (54%; p=0.005), and leptin (17%; p=0.025). The present study demonstrated positive effects of RJ administration on lipid profile, satiety, inflammation, and antioxidant capacity in overweight adults. Therefore, our study supports the benefits of RJ supplementation for the improvement of human health. PMID: 31312222 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

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Abstract Non-Alcoholic Fatty Liver Disease (NAFLD), the most common liver disease, is characterized by accumulation of fat (>5% of the liver tissue), in the absence of alcohol abuse or other chronic liver diseases. Its prevalence is increasing because of obesity, metabolic syndrome or Type 2 Diabetes Mellitus (T2DM). NAFLD can cause liver inflammation and progress to Non-Alcoholic Steatohepatitis (NASH), fibrosis, cirrhosis or Hepatocellular Cancer (HCC). Nevertheless, Cardiovascular Disease (CVD) is the most common cause of morbidity and mortality in NAFLD/NASH patients. Current guidelines suggest the use of p...
Source: Current Vascular Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Curr Vasc Pharmacol Source Type: research
Publication date: October 2019Source: Journal of Functional Foods, Volume 61Author(s): Jordi Mayneris-Perxachs, Juan Maria Alcaide-Hidalgo, Esther de la Hera, Josep Maria del Bas, Lluís Arola, Antoni CaimariAbstractMetabolic syndrome (MetS) has become a major public health concern. Because of their numerous health-promoting biological properties, polyphenols are potential candidates to ameliorate MetS and, recently, the incorporation of these compounds into widely consumed foodstuffs has emerged as a potential strategy to enhance their intake. Therefore, we aimed to assess the potential beneficial effects of biscuit...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
The metabolic syndrome (MetS) is a clustering of abdominal obesity, diabetes and prediabetes, high cholesterol and high blood pressure, that confers an increased risk of cardiovascular disease. There is limite...
Source: Diabetology and Metabolic Syndrome - Category: Endocrinology Authors: Tags: Research Source Type: research
In conclusion, NDGA exerts anti-NASH/anti-fibrotic actions and raises the therapeutic potential of NDGA for treatment of NASH patients with fibrosis and other associated complications.
Source: Molecular and Cellular Endocrinology - Category: Endocrinology Source Type: research
Background and Aims: Non-alcoholic steatohepatitis (NASH) is a major health problem based upon abdominal obesity and metabolic syndrome. An improved mouse model of NASH, such as a choline-deficient high fat diet (CDAHFD)-induced dietary model, has been developed. We, previously, have shown that serum total cholesterol (T-cho) and triglyceride (TG) levels, as well as body weight (BW), were decreased in CDAHFD-induced NASH mice, compared to mice fed standard diet (SD). We, therefore, have explored the molecular mechanisms involved in the reduced serum lipids.
Source: Atherosclerosis - Category: Cardiology Authors: Tags: E-poster session Source Type: research
In a Finnish study that included researchers from UCLA, the DNA from nearly 20,000 people was harnessed to identify genetic mutations that may increase the risk of diabetes, high cholesterol and other diseases and conditions.The findings, published in the journal Nature, suggest the potential for using genomic sequencing to uncover variations that may increase the risk for several common health problems, including heart disease, obesity and metabolic syndrome. The researchers also identified genetic differences that may result in below-average height and weight.The study authors — from UCLA, Washington University, th...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
CONCLUSIONS: The prevalence of MetS in this sample was at least double compared to the general population. Moreover, MetS is associated with increased burden of depression symptoms in this group. Management of early-onset bipolar disorder should integrate strategies focused on modifying MetS risk factors. PMID: 31365195 [PubMed - in process]
Source: Journal of Clinical Psychiatry - Category: Psychiatry Tags: J Clin Psychiatry Source Type: research
Authors: Ahmadi F, Moukhah S, Hosseini R, Maghari A Abstract Objectives: Ultrasonography is a noninvasive and safe modality for assessing body fat and is routinely performed in developed countries. Although pregnant women with obesity are at risk for many unfavorable outcomes, the relationship between abdominal fat distribution and metabolic syndrome (MS) is evident in some studies. Therefore, it is important to evaluate fat thickness in non-obese women and predict MS using fat thickness measurement. Methods: A total of 132 pregnant women completed anthropometric and demographic questionnaires. All women were s...
Source: Oman Medical Journal - Category: Middle East Health Tags: Oman Med J Source Type: research
CONCLUSIONS: MS is correlated with CKD in both premenopausal and postmenopausal women, and the association is dependent on diabetes, hypertension, and hyperuricemia in premenopausal women but not in postmenopausal women. PMID: 31340922 [PubMed - in process]
Source: Journal of Southern Medical University - Category: Universities & Medical Training Authors: Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research
Abstract Metabolic syndrome (MetS) is associated with alterations in coronary vascular smooth muscle and endothelial function. The current study examined the contractile response of the isolated coronary arterioles to serotonin in pigs with and without MetS and investigated the signaling pathways responsible for serotonin-induced vasomotor tone. The MetS pigs (8-weeks old) were fed with a hyper-caloric, fat/cholesterol diet and the control animals (lean) were fed with a regular diet for 12 weeks (n = 6/group). The coronary arterioles (90-180 μm in diameter) were dissected from the h...
Source: Molecular and Cellular Biochemistry - Category: Biochemistry Authors: Tags: Mol Cell Biochem Source Type: research
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