The Effect of Dehydroepiandrosterone (DHEA) Supplementation on IVF or ICSI: A Meta-Analysis of Randomized Controlled Trials.
Conclusion DHEA supplementation improved the outcomes of IVF/ICSI in women with DOR or POR. PMID: 31303658 [PubMed]
CONCLUSIONS: The evidence suggests that sperm selected by hyaluronic acid binding may have little or no effect on live birth or clinical pregnancy but may reduce miscarriage. We are uncertain of the effect of Zeta sperm selection on live birth, clinical pregnancy, and miscarriage due principally to the very low quality of the evidence for this intervention. We are uncertain of the effect of the other selection techniques on live birth, miscarriage, or pregnancy.Further high-quality studies, including the awaited data from the identified ongoing studies, are required to evaluate whether any of these advanced sperm selection...
ConclusionIn the first IVF or ICSI cycle, couples with one pericentric inversion of chromosome 9 in one partner had satisfactory outcomes. The subgroup analysis showed a tendency of better prognosis for the female carrier and inv(9)(p12;q13) type.
In conclusion, high TSH levels (TSH level>2.5 mIU/L) did not affect clinical pregnancy rate or increase miscarriage rate in euthyroid women undergoing IVF/ICSI.
ConclusionsOur data support that a diagnosis of endometriosis, with or without present endometrioma, does not negatively affect ART cumulative results. The impact of endometriosis was discernible on OSI but not on clinical relevant outcomes including pregnancy and LBR.
Male factor infertility is responsible for approximately half of all causes of infertility. In the last decade, more attention has been given to sperm DNA fragmentation (SDF) as a potential cause of unexplained infertility. The increased DNA damage in spermatozoa from men with oligozoospermia seems to be associated with both a reduced chance of natural conception and an increased risk of early pregnancy loss (1). Nevertheless, the role of SDF during in vitro fertilization cycles where intracytoplasmic sperm injection (ICSI) is adopted is still unclear.
ConclusionOur long-term follow-up data demonstrate that the hysteroscopic correction of dysmorphic uteri may result in a high live birth rate in women suffering from unexplained infertility or repeated miscarriages.
ConclusionsIn this study, 11.8% of MAR pregnancies ended in miscarriage. The majority of pregnancy losses occurred in the first trimester and only 0.8 % of the MAR women had a miscarriage after an ultrasound verification of a viable pregnancy at 11-14 weeks of gestation. The corresponding miscarriage rate among SC women was 0.6 %. After adjustment for maternal characteristics, none of the fertility treatment types were associated with an increased risk of miscarriage compared with SC women.
CONCLUSIONS: We could draw no clear conclusions in this systematic review due to the very low to low quality of the evidence reported. PMID: 31236916 [PubMed - as supplied by publisher]
CONCLUSIONS This study showed that the shortened regimen and the ultralong regimen did not produce different pregnancy outcomes after ART, and the single-application, long-term GnRH-a protocol may serve as a cost-effective and safe treatment protocol for EMs patients. PMID: 31187785 [PubMed - in process]
SummaryPolycystic ovary syndrome (PCOS) is one of the most common causes of infertility in women. Progestin-primed ovarian stimulation (PPOS) protocol, which used oral progestin to prevent premature luteinizing hormone (LH) surges in ovarian stimulation, has been proved to be effective and safe in patients with PCOS. The aim of the present study was to compare the efficacy of PPOS protocol with that of the traditional gonadotropin-releasing hormone (GnRH) antagonist protocol in patients with PCOS. A total of 157 patients undergoingin-vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) were recruited into t...