Robot-assisted esophagogastric reconstruction in minimally invasive Ivor Lewis esophagectomy.

Conclusions: Our initial results indicate that Ivor Lewis RAMIE may be a safe and feasible alternative to open and endoscopic Ivor Lewis esophagectomy. PMID: 31285878 [PubMed]
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

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Abstract In recent times, the diagnosis and treatment of superficial laryngopharyngeal cancers has been receiving a lot of attention. Here, we present a case of superficial hypopharyngeal cancer and superficial esophageal cancer for which endoscopic laryngo-pharyngeal surgery (ELPS) and endoscopic submucosal dissection (ESD) were performed simultaneously. The patient was a 67-year-old male. During his follow-up for distal gastrectomy performed earlier for stomach cancer, an upper gastrointestinal endoscopy revealed three primary cancers: superficial hypopharyngeal cancer, superficial esophageal cancer, and esophag...
Source: Journal of Nippon Medical School - Category: Universities & Medical Training Authors: Tags: J Nippon Med Sch Source Type: research
Discussion: This investigative study will provide clinical evidence of BRIHK administration for anxiety and water brash, which might improve mental distress and reduce postoperative mortality. Trial registration: The protocol and progress are registered on the Japan Registry of Clinical Trials (jRCT s021190001) and University Hospital Medical Information Network (UMIN000031330). The protocol was approved by the Japanese Ministry of Health, Labour and Welfare certified clinical research review board, Tohoku University (CRB2180001).
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research
The objective is to start treating chronic diseases from the root and not the symptoms of the disease. As we are starting to enroll patients in "senolytics-clinical trials," it will be imperative to assess if senolysis efficiently targets the primary cause of disease or if it works best in combination with other drugs. Additional basic science research is required to address the fundamental role of senescent cells, especially in the established contexts of disease. Notes on Self-Experimentation with Sex Steroid Ablation for Regrowth of the Thymus
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Introduction: Immune checkpoint inhibitors including nivolumab, an antibody against programmed death-1, have been increasingly introduced in various cancer treatment regimens, and are reported to be associated with immune-related adverse events. Nivolumab-induced renal injury is generally caused by acute interstitial nephritis and is managed by drug discontinuation and steroid therapy. Although this agent can infrequently induce glomerulonephritis, the pathogenesis and therapeutic strategy remain undetermined. Patient concerns: A 78-year-old man was diagnosed with advanced gastric cancer with portal thrombosis. First-...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
(NEW YORK) — As the coronavirus bore down on New York, Dr. Doug Bass’ family begged him to work from home. He refused, pointing to his patients at Phoenix House, a drug and alcohol treatment center where he served as medical director. “He said he was on the front lines and they needed him,” his brother, Jonathan Bass, told The Associated Press. “Too many people relied on him.” Bass, 64, died suddenly last month after suffering symptoms commonly caused by coronavirus, including coughing, a fever and severe stomach cramping. That made him possibly the first physician still treating patient...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 overnight wire Source Type: news
AbstractBackgroundIn April 2017, we launched the multidisciplinary Hamamatsu Perioperative Care Team (HOPE) for all surgical patients. We developed a reinforced intervention strategy, particularly for esophagectomy. We herein report the outcomes of the HOPE at 2  years after commencement.MethodsA total 125 patients underwent esophagectomy and gastric conduit reconstruction for esophageal or esophagogastric junction cancer between January 2014 and December 2018 at the Department of Surgery in Hamamatsu University School of Medicine. The patients were divided into the pre-HOPE group including 62 patients who underwent e...
Source: Esophagus - Category: Gastroenterology Source Type: research
Conclusions: Readmission within 30 days after esophagectomy was determined to be related to postoperative anastomotic leakage and wound problems whereas the vocal cord palsy was not. PMID: 31903259 [PubMed]
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
Abstract BACKGROUND: Postoperative complications after resection of oesophagogastric carcinoma can result in considerable early morbidity and mortality. However, the long-term effects on survival are less clear. METHODS: All patients undergoing intentionally curative resection for oesophageal or gastric cancer between 2006 and 2016 were selected from an institutional database. Patients were categorized by complication severity according to the Clavien-Dindo classification (grades 0-V). Complications were defined according to an international consensus statement. The effect of leak and severe non-leak-related ...
Source: The British Journal of Surgery - Category: Surgery Authors: Tags: Br J Surg Source Type: research
AbstractThe Japanese guideline for gastroenteropancreatic neuroendocrine tumor treatment recommends everolimus or sunitinib as first-line treatment for unresectable pancreatic neuroendocrine tumors (PNETs). Streptozocin (STZ) is recommended as an alternative. We encountered a patient with PNET who had multiple liver metastases and who showed a remarkable response to third-line STZ. The patient was a 50-year-old man with a pancreatic head tumor 32  mm in diameter. We planned to perform subtotal stomach-preserving pancreaticoduodenectomy, but abandoned resecting the pancreas during the surgery upon discovering a small l...
Source: International Cancer Conference Journal - Category: Cancer & Oncology Source Type: research
Abstract In addition to the complications of leprosy, people affected by leprosy (PALs) can suffer from chronic diseases. We evaluated the recent pattern of deaths among Korean PALs and compared it with that in the general population. We analyzed the death certificate data of 1,359 PALs from 2010 through 2013. The all-cause and cause-specific standardized mortality ratio (SMR) and standardized mortality with 95% CI were calculated. Malignancy had the highest standardized mortality, with 130.9 deaths per 100,000 persons, followed by cardiovascular diseases (CVDs; 85.5 deaths) and respiratory diseases (38.2 deaths)....
Source: The American Journal of Tropical Medicine and Hygiene - Category: Tropical Medicine Authors: Tags: Am J Trop Med Hyg Source Type: research
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