Epigenetic modifiers 5-aza-2'-deoxycytidine and valproic acid differentially change viability, DNA damage and gene expression in metastatic and non-metastatic colon cancer cell lines.

In conclusion, 5-aza-dC and VPA can induce different effects in metastatic and non-metastatic cancer cell lines and this may be important in determination of epigenetic profile responsible for metastatic properties of cancer cells. PMID: 31284710 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31284710?dopt=Abstract

Source: Acta Biochim Pol - July 8, 2019 Category: Biochemistry Authors: Ghecham A, Senator A, Pawlowska E, Bouafia W, Błasiak J Tags: Acta Biochim Pol Source Type: research