Fluctuations of sensorimotor processing in migraine: a controlled longitudinal study of beta event related desynchronization

ConclusionIncreased preictal baseline beta activity may reflect a decrease in pre-activation in the sensorimotor cortex. Altered pre-activation may lead to changes in thresholds for inhibitory responses and increased beta-ERD response, possibly reflecting a generally increased preictal cortical responsivity in migraine. Cyclic fluctuations in the activity of second- and third-order afferent somatosensory neurons, and their associated cortical and/or thalamic interneurons, may accordingly also be a central part of the migraine pathophysiology.

Source: The Journal of Headache and Pain - July 8, 2019 Category: Neurology Source Type: research