A Promising Role of Interferon Regulatory Factor 5 as an Early Warning Biomarker for the Development of Human Non-Small Cell Lung Cancer

Lung cancer is the most frequently diagnosed cancer and the leading cause of cancer-related deaths worldwide [1]. Non-small cell lung cancer (NSCLC) accounts for 85%-90% of lung cancer cases and includes two subtypes: lung squamous cell carcinoma and lung adenocarcinoma [2]. The survival of patients with lung cancer is strongly related to the cancer stage as evidenced by a steep decrease in the 5-year overall survival rate from 82% in stage IA to 6% in stage IV [3]. However, in routine clinical practise, many patients with early stage lung cancer are not diagnosed in due time because they are often asymptomatic [4].
Source: Lung Cancer - Category: Cancer & Oncology Authors: Source Type: research