ANKRD26-RET - A novel gene fusion involving RET in papillary thyroid carcinoma

ConclusionsANKRD26-RET is a novel rearrangement of the RET gene, associated with RET expression in thyroid tissue. The result is a fusion of the RET tyrosine kinase to prominent protein-protein interaction motifs. Further studies are required to investigate the influence of different RET rearrangements on metastasis and disease-free survival in PTC.
Source: Cancer Genetics - Category: Cancer & Oncology Source Type: research