EPHA3 enhances macrophage autophagy and apoptosis by disrupting the mTOR signaling pathway in mice with endometriosis.

CONCLUSION: Altogether, EPHA3 could potentially promote the autophagy and apoptosis of macrophages in endometriosis via inhibition of the mTOR signaling pathway, highlighting the potential of EPHA3 as the target to treat endometriosis.
PMID: 31262977 [PubMed - as supplied by publisher]

Source: Bioscience Reports - June 30, 2019 Category: Biomedical Science Authors: Xu H, Gao Y, Shu Y, Wang Y, Shi Q Tags: Biosci Rep Source Type: research