Vitamin D deficiency during pregnancy affects the function of Th1/Th2 cells and methylation of IFN- γ gene in offspring rats.

In conclusion, maternal vitamin D deficiency affected the function of Th1/Th2 cells and methylation of IFN-γ gene in offspring rats. Meanwhile, maternal vitamin D deficiency had the potential to regulate DNMT activity, which may determine the status of methylation.
PMID: 31260744 [PubMed - as supplied by publisher]

Source: Immunology Letters - June 27, 2019 Category: Allergy & Immunology Authors: Jiao X, Wang L, Wei Z, Liu B, Liu X, Yu X Tags: Immunol Lett Source Type: research