Gray matter microglial activation in relapsing vs progressive MS: A [F-18]PBR06-PET study

Conclusions This study suggests that [F-18]PBR06-PET detects widespread abnormal microglial activation in the cerebral gray matter in MS. Increased translocator protein binding in subcortical gray matter regions is associated with brain atrophy and may link to progressive MS.

http://nn.neurology.org/cgi/content/short/6/5/e587?rss=1

Source: Neurology Neuroimmunology and Neuroinflammation - June 30, 2019 Category: Neurology Authors: Singhal, T., O'Connor, K., Dubey, S., Pan, H., Chu, R., Hurwitz, S., Cicero, S., Tauhid, S., Silbersweig, D., Stern, E., Kijewski, M., DiCarli, M., Weiner, H. L., Bakshi, R. Tags: PET, Multiple sclerosis Article Source Type: research