Epigenetic suppression of liver X receptor β in anterior cingulate cortex by HDAC5 drives CFA-induced chronic inflammatory pain

Liver X receptors (LXRs), including LXR α and LXRβ, are key regulators of transcriptional programs for both cholesterol homeostasis and inflammation in the brain. Here, the modes of action of LXRs and the epige...

Source: Journal of Neuroinflammation - June 29, 2019 Category: Neurology Authors: Yu-Jiao Li, Kun Zhang, Ting Sun, Jian Wang, Yan-Yan Guo, Le Yang, Qi Yang, Yan-Jiao Li, Shui-Bing Liu, Ming-Gao Zhao and Yu-Mei Wu Tags: Research Source Type: research