APAP therapy does not improve impaired sleep quality and sympatho-vagal balance: a randomized trial in patients with obstructive sleep apnea and systolic heart failure.

CONCLUSION: Treatment of OSA in patients with systolic HF improves respiratory indices but does not have a favorable effect on sleep quality. While OSA per se was associated with an increase in sympathetic drive, APAP treatment was not associated with a reduction in sympathetic drive. After 6 months of treatment, there was even a trend towards additional increases in sympathetic drive in the APAP group. PMID: 31240541 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31240541?dopt=Abstract

Source: Sleep and Breathing - June 24, 2019 Category: Sleep Medicine Authors: Spiesshoefer J, Aries J, Giannoni A, Emdin M, Fox H, Boentert M, Bitter T, Oldenburg O Tags: Sleep Breath Source Type: research