Role of Near-Infrared Spectroscopy (NIRS) in Intracoronary Imaging

AbstractPurpose of ReviewThe purpose of this article is to review the basic principles of near-infrared spectroscopy (NIRS) and its contemporary role in intracoronary imaging.Recent FindingsNIRS has been demonstrated to effectively detect culprit lesions in acute coronary syndromes (ACS) and to potentially identify vulnerable plaque. Lipid-rich plaques detected by NIRS are also associated with higher incidence of future adverse cardiac events. Plaques with high lipid content detected by NIRS have been shown to predict periprocedural myocardial infarction during percutaneous coronary intervention (PCI). The beneficial effects of high-intensity statin therapy in terms of plaque regression and plaque stabilization have also been demonstrated using NIRS.SummaryNIRS is a valuable intracoronary imaging tool to assess lipid burden in atherosclerotic plaques and has been validated against histopathologic data. The commercially available dual-modality NIRS-intravascular ultrasound (IVUS) catheter further provides complementary data regarding lesion and vessel characteristics, thereby facilitating planning and optimization of PCI. Finally, the ability of NIRS to detect vulnerable plaque opens up potential new opportunities for risk stratification and intensification of secondary preventive measures.
Source: Current Cardiovascular Imaging Reports - Category: Radiology Source Type: research

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Authors: Iyengar SS, Bansal M, Sawhney J, Wander G, Narasingan SN, Chandra KS, D P, Nair T, Krishnakumar B, Deshpande N, Bardoloi N, Shetty S, Desai N, Pancholia AK, Swamy A Abstract The burden of atherosclerotic cardiovascular (CV) disease is alarmingly high and increasing in our country. Dyslipidemia is one of the major modifiable risk factors, and INTERHEART study showed that dyslipidemia had the highest population attributable risk for myocardial infarction. In the management of dyslipidemia, low-density lipoprotein cholesterol (LDL-C) is the primary therapeutic target. In addition to therapeutic lifestyle chan...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
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Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
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Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
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Source: The American Journal of Cardiology - Category: Cardiology Authors: Source Type: research
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Source: American Journal of Cardiovascular Drugs - Category: Cardiology Source Type: research
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Source: International Journal of Cardiology - Category: Cardiology Authors: Source Type: research
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Source: Current Cardiovascular Risk Reports - Category: Cardiology Source Type: research
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Source: Maturitas - Category: Primary Care Authors: Source Type: research
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