PI3K/ Akt/ mTOR pathway as a therapeutic target for colorectal cancer: A review of preclinical and clinical evidence.

CONCLUSION: Inhibitors of the PI3K/mTOR pathway has been successful for the treatment of primary and metastatic colorectal cancers, rendering the pathway as a promising clinical cancer therapeutic target.
PMID: 31215384 [PubMed - as supplied by publisher]

Source: Current Drug Targets - June 17, 2019 Category: Drugs & Pharmacology Authors: Narayanankutty A Tags: Curr Drug Targets Source Type: research