Plant Derived Natural Alkaloids as New Antimicrobial and Adjuvant Agents in Existing Antimicrobial Therapy.

Plant Derived Natural Alkaloids as New Antimicrobial and Adjuvant Agents in Existing Antimicrobial Therapy. Curr Drug Targets. 2019 Jun 18;: Authors: Mittal RP, Jaitak V Abstract Infectious diseases, instigated by pathogenic microorganisms are the cause of numerous health problems in developing countries. Infectious diseases got a place in list of top ten death causes of worldwide. The reason behind that level of severity is antimicrobial resistance. Antimicrobial resistance made the antimicrobial agents useless, that was used in the treatment of infectious diseases. Microbes very smartly achieved the resistance against synthetic and semi-synthetic antimicrobial agents for their survival. So, handling of these infectious diseases becomes very challenging. The resistance developing power is the reason, for their existence from million years. Due to their highly dangerous nature, proper treatment of these infectious diseases becomes a topic of concern. This concern leads the scientists or researchers to focus their research towards natural agents. Plants synthesize secondary metabolites are to cope up with biotic and abiotic changes in environment. Alkaloids are one of the secondary metabolite, synthesized by plants. Alkaloids protect the plant from predators and help them to fight with pathogens. Alkaloids protecting nature can be used as a strong weapon in a battle with resistant microorganisms. The purpose of this review is to provi...
Source: Current Drug Targets - Category: Drugs & Pharmacology Authors: Tags: Curr Drug Targets Source Type: research