Quantitative electrocorticographic biomarkers of clinical outcomes in mesial temporal lobe epileptic patients treated with the RNS ® system.

CONCLUSIONS: ISR is a strong differentiator of clinical response in MTL patients. Normalized theta and gamma also differentiates clinical response. SIGNIFICANCE: In MTL patients, the interictal spike rate along with spectral power computed from chronic ambulatory baseline ECoGs may serve as biomarkers of clinical outcomes and maybe used as treatment endpoints. PMID: 31212202 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31212202?dopt=Abstract

Source: Clinical Neurophysiology - May 30, 2019 Category: Neurology Authors: Arcot Desai S, Tcheng TK, Morrell MJ Tags: Clin Neurophysiol Source Type: research