Role of SOCS3 in enhanced acute-phase protein genes by neonatal macrophages in response to IL-6.

CONCLUSION: Neonatal exhibit an enhanced expression of downstream target genes and IL-6/STAT3 signal pathway which is related with the diminished SOCS3. This provides a new sight into inflammatory responses in neonatal.
PMID: 31204209 [PubMed - as supplied by publisher]

Source: Journal of Microbiology, Immunology, and Infection - May 31, 2019 Category: Microbiology Authors: Chen XF, Wu J, Zhang YD, Zhang CX, Chen XT, Zhao W, Chen TX Tags: J Microbiol Immunol Infect Source Type: research