“886-84-like” tick-borne encephalitis virus strains: Intraspecific status elucidated by comparative genomics

Publication date: Available online 15 June 2019Source: Ticks and Tick-borne DiseasesAuthor(s): Renat AdelshinAbstractTick-borne encephalitis virus (TBEV) can cause severe meningitis, encephalitis, and meningoencephalitis. TBEV represents a pathogen of high zoonotic potential and an emerging global threat. There are three known subtypes of TBEV: Far-Eastern, Siberian and European. Since 2001 there have been suggestions that two new subtypes may be distinguished: “178-79” and “886-84”. These assumptions are based on the results of the envelope gene fragment sequencing (Zlobin et al., 2001; Kovalev and Mukhacheva, 2017) and genotype-specific probes molecular hybridization (Demina et al., 2010). There is only one full-genome sequence of “178-79” strain and two identical ones of “886-84” strain can be found in GenBank. For clarification of the intraspecific position of the "886-84-like" strains group we completely sequenced six previously unknown “886-84-like” strains isolated in Eastern Siberia. As a result of applying different bioinformatics approaches, we can confirm that "886-84-like" strains group is a distinct subtype of TBEV.
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research

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Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
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Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
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Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
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Source: The American Journal of Pathology - Category: Pathology Authors: Tags: Am J Pathol Source Type: research
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