A new heparan sulfate from the mollusk Nodipecten nodosus inhibits merozoite invasion and disrupts rosetting and cytoadherence of Plasmodium falciparum.

CONCLUSIONS: These findings support a potential use for mollusk HS as adjunct therapy for severe malaria. PMID: 31188952 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31188952?dopt=Abstract

Source: Memorias do Instituto Oswaldo Cruz - June 14, 2019 Category: Infectious Diseases Authors: Bastos MF, Albrecht L, Gomes AM, Lopes SC, Vicente CP, de Almeida RP, Cassiano GC, Fonseca RJ, Werneck CC, Pavão MS, Costa FT Tags: Mem Inst Oswaldo Cruz Source Type: research