Laparoscopic procedures in patients with cardiac ventricular assist devices

ConclusionsLaparoscopic abdominal procedures are safe and feasible in patients with LVADs. Although special consideration for bleeding and thrombotic risks, placement of ports and perioperative management is required, the presence of a LVAD itself should not be considered a contraindication for laparoscopic surgery and may in fact be the preferred method for access in these patients.
Source: Surgical Endoscopy - Category: Surgery Source Type: research

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Conclusion: The method provides an analytical solution to estimate the surface field intensity depending on the dipole location and orientation with a negligible computational cost. Significance: This efficient algorithm can be incorporated into an inversion algorithm for localization of wireless endoscopy sensors to allow precise targeted treatment.
Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research
In this study, mouse pulmonary stem/progenitor cells (mPSCs) with capability to differentiate into type I or type II alveolar cells were used as an in vitro cell model to characterize replication and pathogenic effects of influenza viruses in PSCs. First, mPSCs and its immortalized cell line mPSCsOct4+ were shown to be susceptible to PR8, seasonal H1N1, 2009 pandemic H1N1, and H7N9 influenza viruses and can generate infectious virus particles, although with a lower virus titer, which could be attributed by the reduced vRNA replication and nucleoprotein (NP) aggregation in the cytoplasm. Nevertheless, a significant increase...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
AimGuanidinoacetate N-methyltransferase (GAMT) is the second essential enzyme in creatine (Cr) biosynthesis. Short-term Cr deficiency is metabolically well tolerated as GAMT–/– mice exhibit normal exercise capacity and response to ischemic heart failure. However, we hypothesized long-term consequences of Cr deficiency and/or accumulation of the Cr precursor guanidinoacetate (GA).MethodsCardiac function and metabolic profile were studied in GAMT–/– mice>1 year.ResultsIn vivo LV catheterization revealed lower heart rate and developed pressure in aging GAMT–/– but normal lung weight and ...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
More than two million Americans with heart disease are using or have used marijuana - and it could put them at risk of dangerously bleeding or liver damage, a Brigham and Women's study warns.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
New research has shown that by changing the time course of voltage change early when the heart cell contracts it is possible to both withhold a potentially lethal electrical disturbance and improve the strength of cardiac contraction in heart failure at the same time.
Source: University of Bristol news - Category: Universities & Medical Training Tags: Health, International, Research; Faculty of Life Sciences, Faculty of Life Sciences, School of Physiology, Pharmacology and Neuroscience; Press Release Source Type: news
The J.P. Morgan Healthcare conference runs every year in San Francisco, a big draw for the biotech industry, and many organizations take the opportunity to host events at the same time. Among these, the SENS Research Foundation has for the past few years hosted a pitch day in which biotech companies in the longevity industry, largely startups, present to that portion of the Bay Area investor community interested in funding the treatment of aging as a medical condition. I was there to present on progress at Repair Biotechnologies, and took some notes on the other companies as they talked about their work. Kimera Labs ...
Source: Fight Aging! - Category: Research Authors: Tags: Investment Source Type: blogs
This should become the number one priority in public health, writesDr Guru SinghExcellent article by Edward Bullmore in Journal (Inflammation is the new frontier in public health, 20 January). Unfortunately it does not fully explore the role of prevention. It is nowbeing proven that sleep plays a major role in repairing the body, and in particular the brain, especially from the ravages of inflammation. After all, why do we sleep?Inflammation is an essential part of our existence – it’s the way the body responds to an attack from without or within. Unfortunately this also causes damage in other areas, including ...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Sleep Health Society & wellbeing Life and style Mindfulness Mental health Medical research Science Source Type: news
In this study, there was no increased risk of adverse outcomes (including muscle aches, liver dysfunction, new onset of diabetes, cancer, and bleeding strokes), even when LDL was lowered to as low as 20 mg/dL. Although statin medications themselves have been linked to side effects, especially at high doses, it appears that extremely low LDL concentrations are not responsible for side effects. In other words, lowering LDL beyond our previous target of 70 mg/dL appears to be not only safe but beneficial, in patients with CVD. The post LDL cholesterol: How low can you (safely) go? appeared first on Harvard Health Blog.
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Drugs and Supplements Health Heart Health Source Type: blogs
BACKGROUND: Transportation road maintenance and repair workers, or "maintainers," are exposed to hazardous and variable noise levels and often rely on hearing protection devices (HPD) to reduce noise-exposure levels. We aimed to improve upon HPD use as par...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Occupational Issues Source Type: news
Myelin is the sheathing of nerves, essential to their function. Excessive loss produces disabling and ultimately fatal conditions such as multiple sclerosis, but we all lose myelin integrity to some degree as a consequence of the damage and dysfunction of degenerative aging. This most likely contributes to cognitive decline and other age-related issues. A number of different approaches have been identified to boost the operation of the normal maintainance processes that remyelinate nerves, such as FGF21 upregulation, or increasing the size of remyelinating cell populations. Here, researchers discover another possible trigg...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
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